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  • Title: Neurodevelopment in the third year of life in children with antenatal ZIKV-exposure.
    Author: Aizawa CYP, Caron DMR, Souza CB, Kozima PFA, Damasceno L, Einspieler C, Marschik PB, Brasil P, Schmitt ACB, Nielsen-Saines K, Hasue RH.
    Journal: Rev Saude Publica; 2021; 55():15. PubMed ID: 33909869.
    Abstract:
    We report cognitive, language and motor neurodevelopment, assessed by the Bayley-III test, in 31 non-microcephalic children at age 3 with PCR-confirmed maternal Zika virus exposure (Rio de Janeiro, 2015-2016). Most children had average neurodevelopmental scores, however, 8 children (26%) presented delay in some domain. Language was the most affected: 7 children (22.6%) had a delay in this domain (2 presenting severe delay). Moderate delay was detected in the cognitive (3.2%) and motor (10%) domains. Maternal illness in the third trimester of pregnancy and later gestational age at birth were associated with higher Bayley-III scores. Zika-exposed children require long-term follow-up until school age.
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