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  • Title: [Personal experience with high doses of 6-methylprednisolone in human renal transplantation].
    Author: Muolo A, Longo M.
    Journal: Minerva Chir; 1977 Oct 15; 32(19):1197-210. PubMed ID: 339126.
    Abstract:
    Forty rejection episodes were noted in a series of 35 renal transplants. 72.5% were reversible with i.v. 1 g "boluses" of 6-methylprednisolone. Four subjects died during the post-operative period, 10 were subjected to explantation and 21 were discharged with a functioning kidney; of these, mean blood creatinine was 1.02 +/- 0.31 mg in 19. Factors other than rejection influence the results of transplantation. Gastrointestinal, metabolic and bone complications typical of protracted steroid management are examined.
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