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  • Title: Pertussis toxin stimulates delayed-onset, Ca2+-dependent catecholamine release and the ADP-ribosylation of a 40 kDa protein in bovine adrenal chromaffin cells.
    Author: Brocklehurst KW, Pollard HB.
    Journal: FEBS Lett; 1988 Jul 18; 234(2):439-45. PubMed ID: 3391283.
    Abstract:
    Pertussis toxin was found to stimulate catecholamine release from bovine adrenal chromaffin cells in a Ca2+-dependent manner and in the absence of any stimulatory or inhibitory agonists for this cell. The release of catecholamine was associated with the ADP-ribosylation of an approx. 40 kDa protein present in the total membrane fraction. These results are consistent with the existence of an exocytosis-linked G-protein.
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