These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Ultrastructural aspects of the goiter in cog/cog mice.
    Author: Mayerhofer A, Amador AG, Beamer WG, Bartke A.
    Journal: J Hered; 1988; 79(3):200-3. PubMed ID: 3392390.
    Abstract:
    Thyroids of congenitally goitrous (cog/cog) mice were studied with light and electron microscopy. The principal alteration in follicular cells was their largely overdistended rough endoplasmic reticulum (RER). Our findings resemble the ultrastructural features of human hypothyroid goiter caused by a thyroglobulin (TG) defect and thus support the previously suggested abnormalities of TG synthesis and/or processing in cog/cog mice.
    [Abstract] [Full Text] [Related] [New Search]