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  • Title: [Metabolism of prostaglandins in the rat liver during ethanol withdrawal].
    Author: Buko VU.
    Journal: Ukr Biokhim Zh (1978); 1988; 60(2):85-8. PubMed ID: 3394179.
    Abstract:
    The 9-month intake of a 5% ethanol solution as a source of fluid resulted in the essential fatty acid deficiency, a decrease in the prostaglandins E and F2 alpha level and in the activities of the corresponding prostaglandin synthetases and linoleyl-CoA desaturases in the rat liver. Eight days after ethanol withdrawal the indices of prostaglandin metabolism become normal, whereas the arachidonic acid concentration and the linoleyl-CoA desaturase activity increase.
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