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  • Title: Circadian rhythm of histamine metabolism in the rabbit central nervous system (CNS): analysis of brain and ocular structures.
    Author: Nowak JZ, Socko R, Uznanski P.
    Journal: Agents Actions; 1988 Apr; 23(3-4):233-6. PubMed ID: 3394570.
    Abstract:
    The circadian rhythm of the level of histamine (HI) and histidine decarboxylase (HD) and histamine-methyltransferase (HMT) activity in 6 brain and 5 ocular structures of the rabbit was studied. Clear circadian variations of the histaminergic parameters in two brain (hypothalamus and lateral geniculate body) and two ocular (retina and iris-ciliary body) tissues were found. It is suggested that HI in some brain and ocular structures may be functionally involved in activity that depends on circadian rhythm.
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