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  • Title: Segmented simultaneous multi-slice diffusion-weighted imaging with navigated 3D rigid motion correction.
    Author: Riedel Né Steinhoff M, Setsompop K, Mertins A, Börnert P.
    Journal: Magn Reson Med; 2021 Sep; 86(3):1701-1717. PubMed ID: 33955588.
    Abstract:
    PURPOSE: To improve the robustness of diffusion-weighted imaging (DWI) data acquired with segmented simultaneous multi-slice (SMS) echo-planar imaging (EPI) against in-plane and through-plane rigid motion. THEORY AND METHODS: The proposed algorithm incorporates a 3D rigid motion correction and wavelet denoising into the image reconstruction of segmented SMS-EPI diffusion data. Low-resolution navigators are used to estimate shot-specific diffusion phase corruptions and 3D rigid motion parameters through SMS-to-volume registration. The shot-wise rigid motion and phase parameters are integrated into a SENSE-based full-volume reconstruction for each diffusion direction. The algorithm is compared to a navigated SMS reconstruction without gross motion correction in simulations and in vivo studies with four-fold interleaved 3-SMS diffusion tensor acquisitions. RESULTS: Simulations demonstrate high fidelity was achieved in the SMS-to-volume registration, with submillimeter registration errors and improved image reconstruction quality. In vivo experiments validate successful artifact reduction in 3D motion-compromised in vivo scans with a temporal motion resolution of approximately 0.3 s. CONCLUSION: This work demonstrates the feasibility of retrospective 3D rigid motion correction from shot navigators for segmented SMS DWI.
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