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  • Title: Isolated angioedema of the bowel caused by aspirin.
    Author: Osman K, Kendi AT, Maselli D.
    Journal: Clin J Gastroenterol; 2021 Aug; 14(4):1096-1102. PubMed ID: 33999375.
    Abstract:
    Angioedema is a self-limited, localized tissue swelling, resulting from fluid extravasation into interstitial spaces. It may occur in isolation or be accompanied by urticaria and/or anaphylaxis. The phenomenon has been linked to multiple medications, including non-steroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme inhibitors (ACEIs). NSAID-induced angioedema is observed in < 0.3% of patients taking NSAIDs. While isolated visceral angioedema has been reported from ACEIs, it has not been documented from NSAID use, particularly aspirin usage. Here, we report a case of isolated visceral angioedema attributed to aspirin use.
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