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  • Title: Pre-operative embolization for staged treatment of infantile choroid plexus papilloma.
    Author: Mangham WM, Elijovich L, Lee-Diaz JA, Orr BA, Gienapp AJ, Boop FA.
    Journal: Childs Nerv Syst; 2022 Feb; 38(2):429-433. PubMed ID: 34009420.
    Abstract:
    Choroid plexus papillomas (CPPs) are benign but rare neuroepithelial neoplasms of the choroid plexus that represent the non-malignant form of a spectrum of tumors of the choroid plexus. The vast majority of CPPs present in children under 5 years of age. Some CPPs are diagnosed prenatally, but many of them reach a large size before diagnosis. CPPs typically present with signs and symptoms of hydrocephalus. Treatment of these tumors has traditionally been with surgical resection. Large CPPs in young children present a challenge due to risk of high blood loss during resection. Here, the authors describe the case of a 3-month-old presenting with hydrocephalus and a large CPP of the third ventricle that was managed with a staged strategy of embolization followed by a delayed resection, allowing the tumor to involute prior to surgery.
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