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  • Title: [Use of urea in the treatment of patients with suppurative diseases of the lungs and pleura].
    Author: Kolos AI, Nenaidenko EV.
    Journal: Vestn Khir Im I I Grek; 1988 Mar; 140(3):71-3. PubMed ID: 3407080.
    Abstract:
    Under analysis were results of treatment of 96 patients with suppurative diseases of the lungs and pleura. The 30% solution of urea was locally used in 59 patients as pleural punctures, introduction of the solution through drains into the purulent cavity by dropping irrigation of bronchi and tamponage of open purulent cavities. Gram-positive microorganisms were found to die in the 30% solution of urea within 30 min.--3 h, gram-negative ones--within 30 min.--1 h. The introduction of urea directly into the purulent infection focus against the background of general therapy allowed to quickly block the acute phase of the suppurative process, to prepare the patients to planned operations and to reduce the amount of postoperative complications as compared with a control group of patients who were treated by routine local antiseptic drugs.
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