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  • Title: [Value of stress and long-term ECG in the diagnosis of silent myocardial ischemia in patients with coronary heart disease].
    Author: Hausmann D, Nikutta P, Daniel WG, Hartwig CA, Wenzlaff P, Lichtlen PR.
    Journal: Z Kardiol; 1988 May; 77(5):282-90. PubMed ID: 3407272.
    Abstract:
    Symptomatic and asymptomatic myocardial ischemia during exercise testing and during daily activities (ST-segment analysis on 24-h Holter ECG) was studied in 109 patients with stable angina pectoris and proven coronary artery disease (coronary stenoses greater than 70%) (group I) and in 20 patients with angiographically normal coronary arteries or minimal changes (group II). During exercise testing, 94/109 (86.2%) group I patients and 6/20 (30%) group II patients showed ST-segment depression greater than or equal to 0.1 mV. During Holter ECG, transient ST-segment depression (greater than or equal to 0.1 mV; greater than or equal to 1 min) was observed in 76/109 (69.7%) group I patients and in 5/20 (25%) group II patients; all patients with positive Holter ECG also had a positive exercise tests result. Heart rate and exercise duration at the onset of ischemia during stress testing were useful parameters to estimate the incidence of ischemic episodes during Holter ECG. Patients with asymptomatic positive exercise tests showed a significantly higher percentage of asymptomatic ischemic episodes during Holter ECG than patients with a symptomatic positive exercise test (89% vs. 68% asymptomatic ischemic episodes; p less than 0.001). Therefore, in patients with coronary artery disease and stable angina pectoris, the exercise test provides information also about the activity of ischemic heart disease during daily activities.
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