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  • Title: Neurologic manifestations associated with hypothyroidism in four dogs.
    Author: Bichsel P, Jacobs G, Oliver JE.
    Journal: J Am Vet Med Assoc; 1988 Jun 15; 192(12):1745-7. PubMed ID: 3410793.
    Abstract:
    Hypothyroidism was believed responsible for peripheral and central neurologic abnormalities in 4 dogs. Clinical signs consisted of abnormalities of gait and postural reactions and dysfunction of multiple cranial nerves in all 4 dogs. Circling, hypermetria, and spontaneous verticle nystagmus were observed in some of the dogs. Hypothyroidism was diagnosed in all 4 dogs on the basis of low resting serum thyroxine concentration and inadequate response to thyroid stimulating hormone. After thyroid hormone supplementation, resolution of neurologic abnormalities was complete in 2 dogs and partial in the other 2 dogs.
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