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  • Title: Primary structure of neuromedin U from the rat.
    Author: Conlon JM, Domin J, Thim L, DiMarzo V, Morris HR, Bloom SR.
    Journal: J Neurochem; 1988 Sep; 51(3):988-91. PubMed ID: 3411332.
    Abstract:
    The primary structure of neuromedin U from the rat ileum was established as: Tyr-Lys-Val-Asn-Glu5-Tyr-Gln-Gly-Pro-Val10-Ala-Pro-Ser-Gly-+ ++Gly15-Phe-Phe-Leu- Phe-Arg20-Pro-Arg-Asn.NH2. There was no evidence for microheterogeneity. This amino acid sequence contains two deletions and nine substitutions compared with the neuromedin U-25 from the pig. In particular, the replacement of the Arg16-Arg17 processing site in the porcine peptide by Gly14-Gly15 in the rat means that a peptide corresponding to neuromedin U-8 was not found in the rat intestine.
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