These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antigenic cross-reactivity between the human whipworm, Trichuris trichiura, and the mouse trichuroids Trichuris muris and Trichinella spiralis.
    Author: Roach TI, Wakelin D, Else KJ, Bundy DA.
    Journal: Parasite Immunol; 1988 May; 10(3):279-91. PubMed ID: 3412784.
    Abstract:
    Cross-reactivity was demonstrated between circulating antibodies from Trichuris trichiura-infected humans and T. muris-infected mice for heterologous antigen preparations. Mouse immune sera raised against excretory/secretory (E/S) products and anterior end homogenate from adult T. muris showed marked affinity for T. trichiura adult homogenate in ELISA, and 35S-methionine-labelled adult T. muris E/S products were precipitated by T. trichiura infection sera. Monoclonal antibodies recognizing a 48 kD Trichinella spiralis muscle larval beta-stichocyte granule antigen also showed avidity for T. trichiura adult homogenate in ELISA, as did serum from mice with patent T. muris worm burdens. This cross-reactivity is thought to result from shared stichocyte antigens and the relevance of this observation is discussed.
    [Abstract] [Full Text] [Related] [New Search]