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  • Title: The value of immunoreactive lipase in acute pancreatitis.
    Author: Hemingway DM, Johnson I, Tuffnell DJ, Croton RS.
    Journal: Ann R Coll Surg Engl; 1988 Jul; 70(4):195-6. PubMed ID: 3415167.
    Abstract:
    We have evaluated a new agglutination test for serum immunoreactive lipase in 24 patients with abdominal pain and hyperamylasaemia. On admission all 20 patients with acute pancreatitis had a positive lipase test, 3 of the 4 patients who did not have pancreatitis had a negative lipase test. The sensitivity of the lipase test on day 1 is 100%, the specificity 96% and predictive value of a positive test is 95.2% compared to 83% for amylase. A negative test excludes pancreatitis. In addition, the test stays positive longer than hyperamylasaemia.
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