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  • Title: Tumor-like Lesions in Patients with Granulomatosis with Polyangiitis: A Case Series.
    Author: Gendelman O, Kuntzman Y, Shovman O, Langevitz P, Tsur AM, Erez D, Levy Y, Amital H.
    Journal: Isr Med Assoc J; 2021 Jun; 23(6):350-352. PubMed ID: 34155847.
    Abstract:
    BACKGROUND: Granulomatosis with polyangiitis (GPA) is a rare small vessel vasculitis. It usually involves the respiratory tract and kidney. Rarely, tumor-resembling inflammatory changes ensue. OBJECTIVES: To report three unique cases of GPA presenting with tumor-like lesions in various organs. METHODS: We presented three cases of GPA. Case 1 presented with typical upper respiratory symptoms of GPA and a mediastinal mass. Case 2 presented with low back pain, a large retroperitoneal mass, and nodular skin lesions. Case 3 presented with epigastric pain and a paravertebral inflammatory mass. RESULTS: The patients were treated successfully with rituximab. CONCLUSIONS: Clinicians should be aware of this presentation of granulomatosis with polyangiitis, which is known as Tumefaction Wegener's granulomatosis.
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