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  • Title: Kinetic independence between red cell anion exchange and urea transport.
    Author: Fröhlich O, Jones SC.
    Journal: Biochim Biophys Acta; 1988 Sep 01; 943(3):531-4. PubMed ID: 3415994.
    Abstract:
    Urea equilibrium exchange fluxes were measured in human red cells under conditions which recruit the anion transporter into an outward-facing or an inward-facing state (with respect to the anion transport site). Regardless of these conditions, urea transport always occurred at the same rate: 41 +/- 2 mol.(kg cell solids.min)-1 with 1.5 M urea at 0 degrees C. These data suggest that the pathway on the band-3 protein which mediates anion transport is kinetically uncoupled from urea transport and is probably not involved in the transport of urea across the red cell membrane.
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