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  • Title: [Energy metabolism in the erythrocytes of humans exposed to anti-orthostatic hypokinesia].
    Author: Vorob'ev VE, Ivchenko VF, Stazhadze LL.
    Journal: Kosm Biol Aviakosm Med; 1988; 22(3):39-41. PubMed ID: 3419117.
    Abstract:
    Energy metabolism in red blood cells of men exposed to antiorthostatic hypokinesia (-8 degrees) was investigated. It was found that during this exposure erythrocytes synthesized organic phosphates such as diphosphoglyceric acid (2,3-DPG), ATP and ADP that were similar in terms of their effect on hemoglobin affinity for oxygen. On hypokinesia day 6, when the oxygen concentration in the erythrocyte environment increased, the content of the above phosphates also grew. It can therefore be concluded that glucose metabolism in erythrocytes of test subjects exposed to antiorthostatic hypokinesia is implemented via enhanced interaction between glycolytic and pentose-phosphate pathways.
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