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  • Title: Effects of adrenaline and the concentration of solution on extradural block with etidocaine.
    Author: Buckley FP, Littlewood DG, Covino BG, Scott DB.
    Journal: Br J Anaesth; 1978 Feb; 50(2):171-5. PubMed ID: 341935.
    Abstract:
    Forty patients allocated to four groups received extradural injections of etidocaine for the performance of lower abdominal surgery. Twenty millilitre of the 1% or 1.5% solutions with or without adrenaline (1:200 000) was given in a double-blind manner. The addition of adrenaline to etidocaine did not significantly prolong the duration of analgesia, but it produced significant more motor block. Etidocaine 1.5% caused significantly longer durations of analgesia and more motor block than the 1% solution. The spread of sensory analgesia was similar with all four solutions of local anaesthetic agent.
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