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  • Title: Hemolytic activity of and lethal toxin production by environmental strains of Vibrio parahaemolyticus.
    Author: Sarkar BL, Kumar R, De SP, Pal SC.
    Journal: Appl Environ Microbiol; 1987 Nov; 53(11):2696-8. PubMed ID: 3426228.
    Abstract:
    Repeated subculturing of Kanagawa-negative strains of Vibrio parahaemolyticus on Wagatsuma agar induced the production of a hemolysin which was not the thermostable direct hemolysin. Crude hemolysin exhibited a 30 to 40% lethal toxicity in mice after intraperitoneal injection. A 21-kilodalton protein band was observed with all the environmental isolates in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Results suggested that a certain percentage of environmental strains of V. parahaemolyticus is responsible for pathogenesis.
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