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  • Title: A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat.
    Author: Delamere NA, Williams RN.
    Journal: Comp Biochem Physiol B; 1987; 88(3):847-9. PubMed ID: 3427921.
    Abstract:
    1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0 degrees C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.
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