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  • Title: Binding of the bovine pancreatic secretory trypsin inhibitor (Kazal) to bovine serine (pro)enzymes.
    Author: Menegatti E, Guarneri M, Bolognesi M, Ascenzi P, Amiconi G.
    Journal: J Mol Biol; 1987 Nov 05; 198(1):129-32. PubMed ID: 3430603.
    Abstract:
    The effect of temperature and pH on the association equilibrium constant (Ka) for the binding of the bovine pancreatic secretory trypsin inhibitor (bovine PSTI, type I; Kazal inhibitor) to bovine beta-trypsin, bovine alpha-chymotrypsin and bovine trypsinogen has been investigated. The results suggest that serine (pro)enzyme inhibitor interaction involves both rigorous spatial configuration and molecular flexibility.
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