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  • Title: [Is the theoretical blood volume the optimum for chronic respiratory insufficiency? Hemodynamic study of chronic bronchitis patients as a function of the hematocrit].
    Author: Redondo J, Henriquez A, Schrijen F, Delorme N, Georges F.
    Journal: Rev Mal Respir; 1987; 4(5):251-5. PubMed ID: 3432713.
    Abstract:
    We have studied oxygen transport and haemodynamics in 19 clinically stable chronic bronchitis split into two groups with comparable blood gases but different haematocrits (Group I = 33%, Group II = 51.5%). The aim of the study was to assess the suitability of bringing the blood volume down to the predicted normal value by repeated venesection. The respiratory function was moderately altered in these patients. The pulmonary and systemic vascular resistance were significantly more elevated in Group II. The arterial oxygen transport was comparable in the two groups. On the other hand for Group I the systolic work of the right ventricle was greater on account of the increased cardiac output. We have not observed any difference in blood volume between the two groups of patients. These results suggest that a return to the predicted blood volume is not recommended without some doubts in chronic bronchitis with polycythaemia.
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