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  • Title: [Evaluation of the effect of arginine vasopressin on the formation of the conditioned reaction of active avoidance in rats].
    Author: Titov SA, Nikonova AB.
    Journal: Zh Vyssh Nerv Deiat Im I P Pavlova; 1987; 37(5):922-8. PubMed ID: 3433936.
    Abstract:
    The effect was studied of arginine-vasopressin (AVP) intraperitoneal administration in a doze of 0.001 mg/kg on elaboration of conditioned reaction (CR) of active avoidance in rats. Estimation of reaction dynamics by dynamic delta index allowed to increase the informational value of the experimental data with taking into account the direction of reaction shift and individual characteristic of the animal. AVP improved the elaboration of active avoidance CR, lowered variability of individual learning ability and did not influence the change of the number of intersignal reactions and short-latency escapes in the process of learning. It is suggested that the main site of AVP effect is the animal's reaction to conditioned sound stimulus.
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