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  • Title: [Cardiovascular effects of histamine mediated by H1- and H2-receptors].
    Author: Mokhort NA, Seredinskaia NN.
    Journal: Farmakol Toksikol; 1987; 50(6):55-8. PubMed ID: 3436426.
    Abstract:
    Histamine was found to suppress the myocardial contractile function, to decrease systemic arterial blood pressure and to exert a positive chronotropic effect in unanesthetized dogs. A preliminary blockade of H1-receptors prevented the hypotensive effect of histamine, blockade of H2-receptors prevented the development of the positive chronotropic effect.
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