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  • Title: Chemical "Butterfly Effect" Explaining the Coordination Chemistry and Antimicrobial Properties of Clavanin Complexes.
    Author: Miller A, Matera-Witkiewicz A, Mikołajczyk A, Wieczorek R, Rowińska-Żyrek M.
    Journal: Inorg Chem; 2021 Sep 06; 60(17):12730-12734. PubMed ID: 34382773.
    Abstract:
    Can a minor difference in the nonmetal binding sequence of antimicrobial clavanins explain the drastic change in the coordination environment and antimicrobial efficiency? This study answers the question with a definite "yes", showing the details of the bioinorganic chemistry of Zn(II) and Cu(II) complexes with clavanins, histidine-rich, antimicrobial peptides from hemocytes of the tunicate Styela clava.
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