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  • Title: [Medical treatment of metastatic cancer of the kidney with a combination of vinblastine and recombinant interferon alpha IIa. Result of a phase I-II trial].
    Author: Jacqmin D, Bergerat JP, Dufour P, Bollack C, Prévot G, Jurascheck F, Bailly G, Degaris S, Oberling F.
    Journal: J Urol (Paris); 1987; 93(8):463-6. PubMed ID: 3440838.
    Abstract:
    Usual treatments of metastatic renal cell carcinoma are not efficient. Phase II trials using Interferon alpha showed a low response rate (10 to 15%). We have conducted a phase I-II trial using a combination of Vinblastine and Recombinant alpha 2 A Interferon in 21 patients. The response rate is of 43% including 1 complete and 8 partial remissions, 5 stabilizations and 8 progressive diseases. In spite of important side effects, these results are promising.
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