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  • Title: [Anti-insulin antibodies and circulating immune complexes in patients with diabetes mellitus].
    Author: Efimov AS, Malyzhev VA, Sakalo EA.
    Journal: Ter Arkh; 1987; 59(11):15-8. PubMed ID: 3441859.
    Abstract:
    The authors presented the results of a study of the levels of circulating immune complexes and antiinsulin antibodies in patients with diabetes mellitus with regard to the main clinical characteristics of disease. The level of immune complexes was shown to reflect the gravity of disease and a degree of renal and reticular vascular lesion. This relationship was most noticeable in patients with type I and type II diabetes mellitus on insulin therapy. In 30-40% of patients with diabetic microangiopathies of different sites an increase in the content of immune complexes was undetectable.
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