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Title: A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3. Author: Lundin LG. Journal: Biochem Genet; 1987 Aug; 25(7-8):603-10. PubMed ID: 3447593. Abstract: A gene (Bmn) with a major effect on beta-mannosidase activity in kidney and liver of the house mouse was revealed by assay with the synthetic substrate p-nitrophenyl-beta-D-mannoside. Activity is low in DBA/2J and CSB mice and high in C57BL/6J mice. By the use of the BXD series of recombinant inbred strains and by crosses between C57BL and CSB, it was possible to map the gene to the distal part of chromosome 3 by demonstration of linkage to a gene for cadmium resistance, cdm, as well as to the Adh-3 locus.[Abstract] [Full Text] [Related] [New Search]