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  • Title: Chemical constituents of Impatiens chapaensis Tard. and their α-glucosidase inhibition activities.
    Author: Linh NTT, Thuy TT, Tam NT, Cham BT, Tam KT, Sa NH, Thao DT, Chinh VT, Anh NTH.
    Journal: Nat Prod Res; 2022 Jun; 36(12):3229-3233. PubMed ID: 34498968.
    Abstract:
    Sixteen compounds (1-16) were isolated from Impatiens chapaensis. Chemical structures were determined by spectroscopic analyses and comparisons with previously published data. This report is the first to identify compounds 1, 5-7, 10, 12-14, and 16 from the genus Impatiens. Seven chosen isolates (5, 7, 10, 11, 12, 15, and 16) were submitted for α-glucosidase inhibition assays with acarbose as the positive control (IC50 = 227.14 ± 13.71 µM). Flavonoid 5 exhibited a significant inhibitory effect (IC50 = 101.00 ± 9.01 µM).
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