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  • Title: [Transplantation pneumonology].
    Author: Hoyer J.
    Journal: MMW Munch Med Wochenschr; 1978 Feb 10; 120(6):167-70. PubMed ID: 345114.
    Abstract:
    The importance of the lung in graft surgery is essentially characterized by three points: infection in immunosuppression, transplantation lung and the transplant. The therapeutic reduction of endogenous defense increases the risk of infection considerably. Every hint of pulmonary infection in the patient with a transplant demands a thorough diagnostic investigation, even operative measures not being excluded in the course of clarification. The phenomenon of "transplantation lung" is probably caused by circulating antigen-antibody complexes. In lung transplantation, difficulties begin in obtaining a satisfactory organ, most donors with cerebral death cannot be considered. Immune-induced changes of the hemostasis system lead to microemboli and extravasation into the alveolar space. The risk of infection is greatest here, because the transplant is in constant communication with the outside world.
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