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  • Title: Results of bronchial challenge after infantile obstructive bronchitis.
    Author: Póder G, Kelemen J, Mezei G, Börzsönyi L.
    Journal: Acta Paediatr Hung; 1987; 28(3-4):201-7. PubMed ID: 3454207.
    Abstract:
    The bronchial hyperreactivity was examined in a follow-up of 206 children having had obstructive bronchitis before two years of age. The acetylcholine challenge was done with 0.5% and 1% Pharmalgen solutions. The bronchial hyperreactivity was established over a 20% decrease of PEF and/or FEV1 values. Summarizing the results produced by 0.5% and 1% solutions a significant difference could be found in the bronchial hyperreactivity between the follow-up and control groups. Similarly the PC20 (provocative concentrations) values were suitable for differentiating the two groups. Upon physical exercise, EIB occurred in 2%. With the skin prick test (SPT) by 10 allergens 3+ or 4+ positivity was found in 17% of the children. Between the bronchial hyperreactivity and SPT positivity a significant correlation could be established.
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