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  • Title: Localization of the human haptoglobin genes distal to the fragile site at 16q22 using in situ hybridization.
    Author: Simmers RN, Stupans I, Sutherland GR.
    Journal: Cytogenet Cell Genet; 1986; 41(1):38-41. PubMed ID: 3455911.
    Abstract:
    The distamycin A-sensitive fragile site fra(16)(q22) is a precisely localized chromosomal marker. When expressed at metaphase, it visibly separates the chromosome material on either side of the fragile site. Using a cDNA probe encoding both the alpha and beta haptoglobin chains, the haptoglobin loci were found by in situ hybridization to be distal to fra(16)(q22).
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