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  • Title: [Validation of a contact-free sleep apnea monitor in adults with obstructive sleep apnea].
    Author: Xue JB, Zhao R, Li J, Zhao L, Zhou B, Dong XS, Han F.
    Journal: Zhonghua Jie He He Hu Xi Za Zhi; 2021 Oct 12; 44(10):880-885. PubMed ID: 34565114.
    Abstract:
    Objective: To evaluate the diagnostic value of a contact-free sleep apnea monitor in Chinese adults with obstructive sleep apnea (OSA). Methods: One hundred and ninety-eight participants with snoring were recruited between July 2018 and May 2019 in Sleep Center of Peking University People's Hospital, using nocturnal polysomnography (PSG) and contact-free sleep apnea monitor simultaneously. We evaluated the difference between respiratory event index (REI) generated by contact-free sleep apnea monitor and PSG-Apnea-Hypopnea Index (AHI). We calculated the sensitivity and specificity of OSA diagnosis using the contact-free sleep apnea monitor by hypothesis testing for means, Pearson correlation coefficient and Bland-Altman plots. Then, we used the receiver operating characteristic (ROC) curve to find out the best cut-off of OSA diagnosis. Results: PSG-AHI and the REI of contact-free sleep apnea monitor showed no statistically significant difference [15.9 (4.7, 40.2) vs. 16.2 (6.1, 40.0), P=0.381], and they were significantly correlated (r=0.914, P<0.05), with mean difference of -0.06 (95%CI:-18.44, 18.31). The ROC curve showed that if REI ≥5 events/h was used as diagnostic criteria, the sensitivity and specificity of diagnosing OSA were 91.2% and 58.0%, respectively. The sensitivity and specificity of the contact-free sleep apnea monitor REI≥13.3 in diagnosing moderate and severe OSA were 90.1% and 71.1%, respectively. Conclusion: The REI obtained from the contact-free sleep apnea monitor showed a good agreement with the PSG-AHI, and therefore, the contact-free sleep apnea monitor can be used for the screening of patients with moderate and severe OSA. 目的： 评价非接触式睡眠呼吸监测仪在成人阻塞性睡眠呼吸暂停（OSA）患者中的应用价值。 方法： 本研究选取2018年7月至2019年5月因打鼾就诊于北京大学人民医院睡眠中心的成人患者，在进行多导睡眠监测（PSG）的同时使用非接触式睡眠呼吸监测仪进行监测，利用均数检验、Pearson相关系数及Bland-Altman法评估非接触式睡眠呼吸监测仪生成的呼吸事件指数（REI）与PSG生成的呼吸暂停低通气指数（AHI）之间的一致性，计算非接触式睡眠呼吸监测仪诊断OSA的敏感度和特异度，并以受试者工作特征（ROC）曲线确定其诊断OSA的最佳界值。 结果： 共纳入198例患者，其中男120例，女78例，年龄45.5（33.0，57.3）岁。PSG生成的AHI与非接触式睡眠呼吸监测仪的REI差异无统计学意义［15.9（4.7，40.2）次/h比16.2（6.1，40.0）次/h，P=0.381），二者显著相关（r=0.914，P<0.05），其一致性检验的平均差-0.06次/h（95%CI：-18.44~18.31）；如以REI≥5次/h作为诊断标准，则非接触式睡眠呼吸监测仪诊断OSA的敏感度为91.2%，特异度为58.0%；以REI≥13.3次/h诊断中重度OSA的敏感度、特异度分别为90.1%，71.1%。 结论： 该非接触式睡眠呼吸监测仪所得REI与PSG-AHI一致性较好，可用于OSA及中重度OSA患者的筛查。.
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