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  • Title: [Monoblastic (M5a) form of relapse in acute myeloblastic (M2) leukemia with t(8;21)].
    Author: Daniel MT, Bernheim A, Garand R, Bray B, Leverger G, Flandrin G, Berger R.
    Journal: Nouv Rev Fr Hematol (1978); 1986; 28(2):115-7. PubMed ID: 3461425.
    Abstract:
    An exceptional case of acute myeloblastic leukemia (M2) with t(8;21) relapsed as an acute monoblastic leukemia (M5). At that time only a minority of metaphases exhibited a t(8;21) and/or abnormality of chromosome No 11 long arm whereas various other chromosomal changes were present. The existence of a relapse of M2 with t(8;21) as M5 is discussed in relation to the commitment of the cells which became leukemic, and to the possibility of a second leukemia.
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