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  • Title: [Radiation protection of mice with hypoxic gas mixtures after administration of anti-hypoxic agents].
    Author: Waĭnson AA, Uriupov OIu.
    Journal: Radiobiologiia; 1986; 26(3):329-33. PubMed ID: 3461496.
    Abstract:
    It is shown that such substances as gutimine, antizol and mexamine increases the resistance of animals to short-term breathing of gas mixtures containing 6 and 5% oxygen. Even if some of them decrease the degree of radioprotective effect of hypoxia, they afford the possibility to safe use of breathing mixtures with lower oxygen content than endured by intact animals, with the resulting increase in radioprotection. Thus the antihypoxic substances can be tested during hypoxiradiotherapy of human tumors.
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