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  • Title: New variant translocation (1;8;21) in a case of acute myeloblastic leukemia (M2).
    Author: Taguchi H, Kitagawa T, Yamashita M, Kubonishi I, Miyoshi I.
    Journal: Cancer Genet Cytogenet; 1986 Nov; 23(3):219-23. PubMed ID: 3464341.
    Abstract:
    A new translocation involving chromosome #1, #8, and #21 in a patient with type M2 acute myeloblastic leukemia is reported. The breakpoint of #1 in this case was at band p13 and differed from that in two previously reported cases of t(1;8;21) involving the long arm of #1. A key event leading to the development of the M2 phenotype appears to be a break at band q22 of #8 with associated translocation of the terminal end of the long arm of #21.
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