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  • Title: The therapeutic effectiveness of nitrous oxide and chloral hydrate administered orally, rectally, and combined with hydroxyzine for pediatric dentistry.
    Author: Moody EH, Mourino AP, Campbell RL.
    Journal: ASDC J Dent Child; 1986; 53(6):425-9. PubMed ID: 3466914.
    Abstract:
    This study compared the effectiveness of three pediatric sedation modalities when they were used with nitrous oxide. Comparisons were based on a subjective evaluation of the overall quality of the sedation technique and data obtained from a pulse/oximeter. Oral administration of 50 mg/kg of chloral hydrate was the least effective modality.
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