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  • Title: Acute promyelocytic transformation of chronic myeloid leukaemia with an isochromosome 17q.
    Author: van der Merwe T, Bernstein R, Derman D, Stanley A, Dukes I, Murray J, Weaving A.
    Journal: Br J Haematol; 1986 Dec; 64(4):751-6. PubMed ID: 3467788.
    Abstract:
    Transformation to an acute promyelocytic leukaemia occurred in a patient approximately 2 years after having been diagnosed as suffering from chronic myeloid leukaemia (CML). At this time, in addition to the Ph1 chromosomal aberration, an isochromosome 17q [i(17q)] was noted. The t(15:17) was absent. The implications of this are discussed.
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