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  • Title: Induction of cytochrome P-450 mediated mono-oxygenase reactions and conjugation activities in freshwater crayfish (Astacus astacus).
    Author: Lindström-Seppä P, Hänninen O.
    Journal: Arch Toxicol Suppl; 1986; 9():374-7. PubMed ID: 3468918.
    Abstract:
    The inducibility of the freshwater crayfish (Astacus astacus) biotransformation enzymes with model inducers (Aroclor 1254, beta-Naphthoflavone, Phenobarbital) were investigated three days after intra cephalothoracic injection in the fasting crayfish at 5 degrees C. Of the monooxygenase activities, 7-ethoxycoumar in O-deethylase increased in the hepatopancreas significantly (p less than 0.05) after beta-naphthoflavone administration. Benzo(a)pyrene hydroxylase did not change. Aroclor 1254 and phenobarbital injection elevated hepatopancreatic glutathione S-transferase activity (p less than 0.05).
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