These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: 11q-chromosome is associated with abnormal iron stores in myelodysplastic syndromes.
    Author: Mecucci C, Van Orshoven A, Vermaelen K, Michaux JL, Tricot G, Louwagie A, Delannoy A, Van den Berghe H.
    Journal: Cancer Genet Cytogenet; 1987 Jul; 27(1):39-44. PubMed ID: 3472648.
    Abstract:
    Nine cases of myelodysplastic syndrome with a deletion of the long arm of chromosome #11 (11q-) showed ringed sideroblasts, and three of which had an acquired sideroblastic anemia according to the criteria of the FAB classification. In contrast, among four cases of myelodysplastic syndromes with translocation of extra material to the long arm of chromosome #11 (11q+), only one showed bone marrow sideroblasts. These results strongly indicate that an 11q- chromosome is a marker of iron overload in myelodysplastic syndromes. Within the cases of 11q- associated with sideroblastosis, two cytogenetically different anomalies (i.e., terminal or interstitial deletions) were delineated.
    [Abstract] [Full Text] [Related] [New Search]