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Title: Acute tumour lysis syndrome with extreme metabolic abnormalities. Author: Leonov Y, Golik A, Kaufman S, Gilboa Y. Journal: Clin Lab Haematol; 1987; 9(1):85-9. PubMed ID: 3472702. Abstract: Tumour lysis syndrome, manifested by various metabolic derangements, is a known complication after treatment of some lymphoid malignancies. A patient is reported with acute lymphocytic leukaemia who developed a tumour lysis syndrome following intensive chemotherapy. All the known complications of the syndrome were present in the most severe form--hyperuricaemia of 1.44 mmol/l, hyperphosphataemia of 7.7 mmol/l with acute oliguric renal failure and extreme hyperkalaemia of 9.8 mmol/l with electrocardiographic changes. This life-threatening condition did not respond to conservative measures and the patient recovered only after haemodialysis.[Abstract] [Full Text] [Related] [New Search]