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  • Title: [Antibody-dependent cytotoxicity of lymphocytes in acute myeloblastic leukemia and chronic myelocytic leukemia].
    Author: Tishchenko LM, Guseva SA.
    Journal: Eksp Onkol; 1987; 9(2):66-7. PubMed ID: 3472877.
    Abstract:
    Antibody-dependent cytotoxicity (ADC) of peripheral blood blast cells in vitro was studied in 16 patients with acute myeloid leukemia (AML), 6 patients with acute monoblastic leukemia (AMonL), and 13 patients with acute myelomonoblastic leukemia (AMmL). It was found that monoblasts have a higher degree of ADC activities with respect to target cells than myeloblasts. Functional differences between monoblasts and myeloblasts may be used as criteria for differential diagnosis of acute leukemia variants.
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