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  • Title: [Vaccine failure].
    Author: Schaad UB.
    Journal: Schweiz Med Wochenschr; 1987 May 30; 117(22):845-8. PubMed ID: 3474780.
    Abstract:
    The different causes of vaccine failure are presented on the basis of epidemiological definitions and facts. The relevant factors necessary for successful active immunization are potential presence of passively transmitted antibodies, possible interaction with combined vaccine administration, technical requirements, individual immune response, and duration of immunity. Knowledge of these factors often provides the individual explanation for vaccine failure, or serves to prevent it as well as to predict susceptibility to natural infection.
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