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  • Title: Acute promyelocytic leukemia with t(15;17) and t(2;17;15).
    Author: Bjerrum OW, Philip P, Pressler T, Tygstrup I.
    Journal: Cancer Genet Cytogenet; 1987 Sep; 28(1):107-11. PubMed ID: 3475161.
    Abstract:
    Cytogenetic examination in a case of acute promyelocytic leukemia (FAB-M3) demonstrated a stem line with t(15;17) and a side line with t(2;17;15). This observation indicates either clonal evolution from the standard translocation or a de novo complicated translocation. Previous cases with three-way translocations in acute promyelocytic leukemia have been reviewed. Three-way translocations seem to occur with similar frequency in M2 and M3 types of acute myeloid leukemia and in chronic myelocytic leukemia.
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