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  • Title: Adult-onset spinocerebellar syndrome with idiopathic vitamin E deficiency.
    Author: Yokota T, Wada Y, Furukawa T, Tsukagoshi H, Uchihara T, Watabiki S.
    Journal: Ann Neurol; 1987 Jul; 22(1):84-7. PubMed ID: 3477125.
    Abstract:
    A 62-year-old man and his maternal uncle had a selective vitamin E deficiency without generalized fat malabsorption. A progressive neurological disorder comprising ataxia, areflexia, and loss of proprioception developed in their sixth and seventh decades. The vitamin E deficiency is thought to be due to abnormally accelerated utilization, excretion, or degradation of the vitamin. This adult-onset spinocerebellar syndrome is due to vitamin E deficiency not caused by malabsorption.
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