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  • Title: T cell subsets in idiopathic glomerulonephritis.
    Author: Patel R, Connor G, Patel DR, Soriano A, Najera D.
    Journal: Int Arch Allergy Appl Immunol; 1986; 79(2):182-7. PubMed ID: 3484730.
    Abstract:
    Determination of T lymphocyte subsets using monoclonal antibodies revealed a deficiency of suppressor cells and an elevated helper:suppressor T cell ratio in 7 patients with untreated idiopathic immune complex glomerulonephritis and nephrotic syndrome. Possible pathogenetic mechanisms of immunoregulatory cell imbalance and their implications specifically in reference to idiopathic glomerulonephritis are discussed.
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