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Title: Succinic acid fermentation with immobilized Actinobacillus succinogenes using hydrolysate of carbohydrate-rich microalgal biomass. Author: Chiang YY, Nagarajan D, Lo YC, Chen CY, Ng IS, Chang CH, Lee DJ, Chang JS. Journal: Bioresour Technol; 2021 Dec; 342():126014. PubMed ID: 34852448. Abstract: This work aimed to study the efficiency of polyvinyl-alcohol-immobilized Actinobacillus succinogenes ATCC55618 for succinic acid (SA) production. Batch fermentation (pH 7, 45% CO2 gas at 0.04 vvm) using glucose (40 g L-1) resulted in SA titer, 26.7 g L-1; productivity, 3.33 g L-1h-1; yield, 0.621 g g-1. Fed-batch mode with cyclic extrication of SA from the medium markedly enhanced the yield to 0.699 g g-1 and concentration to 59.5 g L-1. Batch fermentation using sugars derived from Chlorella vulgaris ESP-31 without yeast extract gave a SA productivity, concentration, and yield of 1.82 g L-1h-1, 36.1 g L-1, and 0.720 g g-1, respectively. Furthermore, continuous fermentation (at 6 h HRT) with microalgal sugar improved the productivity and yield to 3.53 g L-1h-1 and 0.62 g g-1, respectively, which is comparable to those obtained by using glucose. This study reports the highest productivity for SA fermentation using microalgae-derived sugars.[Abstract] [Full Text] [Related] [New Search]