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  • Title: Modified creatine kinase-MB plots as a tool to detect perioperative myocardial infarction. Evaluation of sensitivity and specificity as compared with electrocardiographic changes.
    Author: Jambroes G, Gimpel JA, Hitchcock JF, Robles de Medina EO, Maas AH.
    Journal: Ann Clin Lab Sci; 1986; 16(3):189-97. PubMed ID: 3487269.
    Abstract:
    Based on electrocardiographic criteria, coronary artery bypass grafting patients were divided into two groups, one with and one without perioperative myocardial infarction. Serial total-creatine kinase activity did not discriminate between the two groups; however, serial creatine kinase-MB activity showed a consistent difference. Patients with perioperative myocardial infarction showed an increase, whereas patients without perioperative myocardial infarction showed a decrease during the postoperative period. The creatine kinase-MB plots showed a sensitivity of 0.92 and a specificity of 0.98 as compared with the electrocardiograms.
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