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  • Title: Induction of antibodies against Newcastle disease virus with syngeneic anti-idiotype antibodies in mice.
    Author: Tanaka M, Sasaki N, Seto A.
    Journal: Microbiol Immunol; 1986; 30(4):323-31. PubMed ID: 3487695.
    Abstract:
    Anti-idiotype antibodies were induced by injecting BALB/c mice with syngeneic antibody against the hemagglutinin of Newcastle disease virus (NDV). These anti-idiotype antibodies were purified and injected into syngeneic mice. Anti-anti-idiotype sera thus prepared contained antibodies against the hemagglutinin of NDV. This NDV-mouse experimental system might provide a good experimental model for investigation of basic problems of idiotype vaccine.
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